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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Child Not Having Sufficient Growth, Chromosome Analysis Done. Can Online Doctor Help?

My daughter is born on 24.08.2000, and now her height is 121 cm only and weight is 30 Kg. Now we made a chromosome check up and the result is "Chromosome analysis(GTG banding) indicates a mosaic karyotype with two cell lines, one with one X Chromosomes found in 60 % of cells and a second cell line with two X chromosomes found in 40% of cells."
Can my child get more height?, if yes How much ?
Wed, 24 Apr 2013
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Pediatrician 's  Response
Hi,
Thanks for your query.
I can appreciate your concerns.
In fact, your daughter has a condition called "mosaic turner" syndrome.
One of the most obvious signs of mosaic Turner syndrome is short stature, which is usually noticed after age 3 .
The injection of growth hormones is usually started during early childhood, or as soon as the condition is diagnosed.
Another symptom that is shared among nearly all women affected by this condition is a lack of sexual changes during puberty.
For instance, the breasts do not usually grow at puberty as they should, and menstrual periods may be absent or irregular. Estrogen replacement therapy may be offered to start breast development and induce periods to begin after puberty.
She needs to see an endocrinologist to start homone therapy as soon as possible.
Hope I have answered your query to your satisfaction.
Best wishes.
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Child Not Having Sufficient Growth, Chromosome Analysis Done. Can Online Doctor Help?

Hi, Thanks for your query. I can appreciate your concerns. In fact, your daughter has a condition called mosaic turner syndrome. One of the most obvious signs of mosaic Turner syndrome is short stature, which is usually noticed after age 3 . The injection of growth hormones is usually started during early childhood, or as soon as the condition is diagnosed. Another symptom that is shared among nearly all women affected by this condition is a lack of sexual changes during puberty. For instance, the breasts do not usually grow at puberty as they should, and menstrual periods may be absent or irregular. Estrogen replacement therapy may be offered to start breast development and induce periods to begin after puberty. She needs to see an endocrinologist to start homone therapy as soon as possible. Hope I have answered your query to your satisfaction. Best wishes.