Hi,I am Dr. Shanthi.E (General & Family Physician). I will be looking into your question and guiding you through the process. Please write your question below.
Could Symbicort Be The Cause For Aneurysmal Dilatation Of Thoracic Aorta?
I have been taking Symbicort 160/4.5 two puffs BID for my Asthma for a few years now. My pulmonologist ordered my Ct thorax six months ago,which she is monitoring periodically for a couple pulmonary nodules on prior CT scans of the Abdomen, and recently, also the chest. This most recent CT thorax, however, unlike the previous CTs, (even the one only six months ago, in November, 2014, which did not reveal this new development) showed a fusiform aneurysmal dilation of the ascending thoracic aorta which measures up to 4 cm in diameter. I also was diagnosed with Ehlers-Danlos Syndrome by a Rheumatologist back on 10/26/2010. But I didn t think that I had the serious form of that genetic/hereditary illness/disorder, although I do seem to have the very soft, stretchy skin, along with the double-jointedness. (Laxity of the joints) My question is, I guess, Could the Symbicort have caused this quick-forming fusiform aneurysmal dilation of the ascending thoracic aorta, or could it have been a contributing factor? Or is it impossible for that to be a causal link, and instead, most likely caused by something else like the Ehlers-Danlos Syndrome? I also have Secondary Adrenal Insufficiency, a pituitary adenoma, a fat-containing adrenal adenoma, some form or another of Autonomic Neuropathy, Congenital absence of thyroid gland, multiple concussions dating back to infancy; and a host of other medical issues. (Some of which resulted from my Closed Head Injury in an Auto Accident on July 25, 2006, and other injuries related to that same accident. So, I know that I gave you a lot of medical history, thinking it might help you tease out an answer to my question.
The reason for your aneurysm of aorta is due to Ehlers-Danlos syndrome and not the medicine which you are taking for asthma as its a connective tissue disease which you would have inherited. The connective tissue provide support to the tissue and due to this lack of support, the aorta has dilated and ballooned out.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Anoop Kumar, General & Family Physician
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Could Symbicort Be The Cause For Aneurysmal Dilatation Of Thoracic Aorta?
Hi, The reason for your aneurysm of aorta is due to Ehlers-Danlos syndrome and not the medicine which you are taking for asthma as its a connective tissue disease which you would have inherited. The connective tissue provide support to the tissue and due to this lack of support, the aorta has dilated and ballooned out. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Anoop Kumar, General & Family Physician