Hello Gurmeet Singh. Thank you for asking at HCM. The facts that your wife gets relieved by inhalers and she gets relief only as long she is taking medicine and she is having frequent breathing problems point towards asthma. Antibiotics do not cure breathlessness of asthma but they cure infections. Sometimes infections are one of many causes of asthma attack. Personally I would suggest your wife to get Spirometry with post-bronchodilator study done which will help to come to diagnosis of asthma. If she has asthma, she should be able to manage her symptoms only with asthma medications and she will need antibiotics only when infection is the cause of her breathlessness. Hope this will be helpful to you. Wish your wife the best of the health. Regards.