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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could Elevated AST And ALT Level Be Indicative Hepatitis Or Cancer?

I received routine blood work back showing an AST of 53 and an ALT of 74. I am hypothyroid, taking 1.0 of Synthroid per day. My TSH came back 6.3. What would cause the elevated AST and ALT? How likely is it that I have hepatitis or cancer? Can the elevated TSH affect the AST and ALT? I am a non-drinker and take no medications except Synthroid (not even Tylenol). I do take calcium cabonate and vitamin D (several hours after the Synthroid dose. I also use Metameucil wafers twice a day (again several hours away from medication). I am a 57 year old, white female. Other tests came back normal. I had a colonoscopy about 4 years ago, and was diagnosed with IBS.
Wed, 4 Jun 2014
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Internal Medicine Specialist,  's  Response
AST and ALT are nonspecific tests, which means they could be elevated for many reasons. That includes both hepatitis or cancer. I don't believe the elevations are related to the high TSH. You are in an age group where chronic hepatitis C is commonly diagnosed. Hepatitis C can cause such elevations without a lot of symptoms. If you were my patient, that is one of the first things I would check. At the same time, you could also be checked for other types of hepatitis. Other problems with your liver or problems with your gallbladder might also cause the elevations. Hope this answers your query. If you have more questions, I would be happy to answer them.
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Could Elevated AST And ALT Level Be Indicative Hepatitis Or Cancer?

AST and ALT are nonspecific tests, which means they could be elevated for many reasons. That includes both hepatitis or cancer. I don t believe the elevations are related to the high TSH. You are in an age group where chronic hepatitis C is commonly diagnosed. Hepatitis C can cause such elevations without a lot of symptoms. If you were my patient, that is one of the first things I would check. At the same time, you could also be checked for other types of hepatitis. Other problems with your liver or problems with your gallbladder might also cause the elevations. Hope this answers your query. If you have more questions, I would be happy to answer them.