I am Targin 10 twice a day and the pain help is reasonable but my body sweats heavily if out in the weather (humidity) and also my tolerance and reaction to situations that I find difficult are very harsh, not my normal behaviour. The sweating is reduced if I am in controlled conditions like keeping to air-conditioning most of the time. The short temper is what worries me the most is this normal. I am also on 60 mg Cymbalta thanks..