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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could Taking Methotrexate For Rheumatoid Arthritis Lead To Red Bumps Under The Skin?

I have rheumatoid arthritis and have a problem with my shins, it started as raised bumps under the skin, then 3 days ago the area now has very small red dots on the raised bumps, also my lower legs are now throbbing, am on methotrexate 25mg weekly and oxycontin 20mg twice daily, I am 59, 5ft 9ins and weigh 9st 12lbs
posted on Fri, 28 Feb 2014
Twitter Fri, 28 Feb 2014 Answered on
Twitter Fri, 28 Feb 2014 Last reviewed on
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Orthopaedic Surgeon,  's  Response
Hello,

I have studied your case.

Yes there can be skin eruption after methotrexate.
Methotrexate is a chemotherapeutic agent having lot of adverse reaction.

Also you are taking large dose of methotrexate.
I will advise to reduce dose to 7.5mg weekly.
You can start combination consulting your treating doctor.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Wishing you good health.

Take care
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Could Taking Methotrexate For Rheumatoid Arthritis Lead To Red Bumps Under The Skin?

Hello, I have studied your case. Yes there can be skin eruption after methotrexate. Methotrexate is a chemotherapeutic agent having lot of adverse reaction. Also you are taking large dose of methotrexate. I will advise to reduce dose to 7.5mg weekly. You can start combination consulting your treating doctor. Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. Wishing you good health. Take care