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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Diabetes, Under Medication. Urine Test Results Increased. Medication Affecting Kidneys?

MY FATHER HAS BEEN TAKING METFORMIN 850 MG 1TABLET 3 TIMES A DAY PLUS GLIZLIPIZIDE XL 10 MGB TWICE A DAY LISINOPRIL TAB 40 MG HCTZ. HE HAS HISTORY OF HTN FOR 43 YRS AND DIABETES 4 YRS AGO MY CONCERN IS THAT HIS URINE EXAMS HAVE BEEN SHOWING UP WITH HIGH ALBUMIN LEVELS. IF HIS GLUCOSE HAS NEVER BEEN ABOVE 200 IN THE PAST 4 YRS IS IT POSSIBLE THAT TOO MUCH MEDICATION IS AFFECTING HIS KIDNEYS.
Mon, 11 Mar 2013
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General & Family Physician 's  Response
Hello,
In normal state there is no protein  found in urine but  if your kidneys are damaged or diseased, albumin may leak into your urine. One of the earliest signs of kidney damage is albumin in your urine.
First of all you should get your 24 hour urine protein estimation done..
If the value of protein in urine in 24 hours is between 30 and 300 ,then it is called as microalbuminaria and is a potentially irreversible stage.
If the level of 24 hour urine protein is above 300 mg,then it is called as overt proteinuria and it is dangerous state ,as it tends to progress to end stage kidney failure very fast.
You should consult your doctor,get 24 hour urine protein and whether micro or macro albuminaria,you should get intensive treatment done which includes intensive control of hypertension and diabetes along with dietary protein and potassium restriction and restriction of medicines toxic o your kidneys like pain killers and certain antibiotics.
Your current medicines don't seem to have role in development of proteins in urine.
Your problem is due to uncontrolled hypertension and diabetes.
Thanks
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Diabetes, Under Medication. Urine Test Results Increased. Medication Affecting Kidneys?

Hello, In normal state there is no protein  found in urine but  if your kidneys are damaged or diseased, albumin may leak into your urine. One of the earliest signs of kidney damage is albumin in your urine. First of all you should get your 24 hour urine protein estimation done.. If the value of protein in urine in 24 hours is between 30 and 300 ,then it is called as microalbuminaria and is a potentially irreversible stage. If the level of 24 hour urine protein is above 300 mg,then it is called as overt proteinuria and it is dangerous state ,as it tends to progress to end stage kidney failure very fast. You should consult your doctor,get 24 hour urine protein and whether micro or macro albuminaria,you should get intensive treatment done which includes intensive control of hypertension and diabetes along with dietary protein and potassium restriction and restriction of medicines toxic o your kidneys like pain killers and certain antibiotics. Your current medicines don t seem to have role in development of proteins in urine. Your problem is due to uncontrolled hypertension and diabetes. Thanks