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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Diagnosed With Fatty Liver And Elevated ALT, AST And Sugar. After Test Suggested Ursocol And Omeprazole. Suggest?

Hello Doctor,
My husband is diagnosed with fatty liver in ultrasound report while he has elevated AST & ALT in blood test report which i am giving here :
1.Total Billirubin : 1.06 mg/dl
2.ALT : 252.3 U/L
3.AST :93.0 U/L
4.LDL cholesterol : 139.14 mg/dl
5.Cholesterol HDL ratio : 6.54

Doctor has suggested him to take ursocol 300 & omeprazole ....& instructed for more blood test which are liver related.his sugar level was also hiked in the report.( first time observed high sugar level) . he is only 29 yrs old.suggest me pls. i m very much worried.
Fri, 27 Sep 2013
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General & Family Physician 's  Response
Hello,
The most common causes for fatty liver and high AST snd ALT are alcohol consumtion,however in absence of alcohol consumtion other reasons which are important are high cholesterol,consumtion of more sugar and diabetes.
In your case,probably high cholesterol and diabetes are responsible for your fatty liver and high liver enzymes.
There is lot of controversy regarding the medication as many gastroenterologist feel that medicines like URSOCOL have no use.
The best and ideal treatment is quit alcohol,if any,control your cholesterol and blood sugar levels,do regular exercises and shed your weight.
Get your liver enzymes tested after 3 months.Most likely you should be all right.
In case,you don't find improvement,consult a gastroenterologist and get yourself tested comprehensively.
Thanks
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Rheumatologist Dr. Venkatesh S Pai's  Response
Hi. The LFT suggests a significant elevation in liver enzymes. This can occur in a number of conditions like alcohol induced liver injury, hepatitis B/C virus induced hepatitis, non-alcoholic steatohepatitis, toxins/ drugs. Further tests are required to rule out/ rule in the various causes of liver injury. This requires a detailed history, physical examination and blood tests. Also his diabetes needs to be controlled if his blood sugar is very high. Alcohol intake should be stopped if he is in the habit. I would suggest that you meet a good gastroenterologist/ hepatologist. Thank you.
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Diagnosed With Fatty Liver And Elevated ALT, AST And Sugar. After Test Suggested Ursocol And Omeprazole. Suggest?

Hello, The most common causes for fatty liver and high AST snd ALT are alcohol consumtion,however in absence of alcohol consumtion other reasons which are important are high cholesterol,consumtion of more sugar and diabetes. In your case,probably high cholesterol and diabetes are responsible for your fatty liver and high liver enzymes. There is lot of controversy regarding the medication as many gastroenterologist feel that medicines like URSOCOL have no use. The best and ideal treatment is quit alcohol,if any,control your cholesterol and blood sugar levels,do regular exercises and shed your weight. Get your liver enzymes tested after 3 months.Most likely you should be all right. In case,you don t find improvement,consult a gastroenterologist and get yourself tested comprehensively. Thanks