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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Diagnosed With Thrombocytosis. Is Weak. Gets Intestinal Bloating. Dropping Platelet Count. Had Quadruple Bypass Surgery. Suggestions?

my 87 yr old mom has been diagnosed with thrombocytosis and is taking 500 mg of hydrea for 10 days so far. she is extremely weak and gets intestinal bloating during the day after eating. will these side effects subside as time goes by. she is very depressed by this. her platelet count was 1284 but has dropped to 1230 within one week of taking hydrea. anything she can do to help these side effects decrease so she can have a better quality of life. 2 and a half years ago she had quadruple bypass surgery but recovered well from that. thank you for any help you can offer.
Thu, 29 Aug 2013
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General & Family Physician 's  Response
Hi, as she is 87 years old there is possibility of side effects to any drugs, or can be the result of the change in the diet. (spicy food)
I to my patient with such bloating prescribes omeprazole, domperidone , along with the other drugs she is using. Thank you.
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Psychiatrist Dr. Anjana Rao Kavoor's  Response
Hi,
Thanks for writing in to us.

Hydroxyurea has active ingredients of hydrea 500 mg. It is used in polycythemia vera, polycythaemia vera, primary thrombocythemia, sickle cell anemia, essential thrombocythaemia. Commonly reported side effects of Hydroxyurea include fever, weakness, nausea, fatigue, nausea and vomiting.

As per data collected out of 3,057 people reported to have side effects when taking Hydroxyurea. Among them, 135 people (4.42%) have Thrombocytopenia.

Hydroxyurea is contraindicated in patients with marked bone marrow depression, i.e., leukopenia (

You may consult your doctor immediately without wasting time.

Hope this helps
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Diagnosed With Thrombocytosis. Is Weak. Gets Intestinal Bloating. Dropping Platelet Count. Had Quadruple Bypass Surgery. Suggestions?

Hi, as she is 87 years old there is possibility of side effects to any drugs, or can be the result of the change in the diet. (spicy food) I to my patient with such bloating prescribes omeprazole, domperidone , along with the other drugs she is using. Thank you.