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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Benadryl And Diphenhydramine Cause Sleeplessness?

I was prescribed benadryl by my doctor for some hitching Iwas have on my hand the pharmacy gave me diphenhydramine by 25 mg. I took one capsule while going to be. This thing had me up all night as if I took some steroid. Th next day I felt so sick so terrible. Why is that
Tue, 30 Jul 2019
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Internal Medicine Specialist 's  Response
Hello,

Benadryl (brand) and Diphenhydramine (generic) are the same. It can cause drowsiness (often transient); sedation but unlikely to cause sleeplessness. Check the date of expiry.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Tushar Kanti Biswas, Internal Medicine Specialist
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Addiction Medicine Specialist Dr. Dr. Matt Wachsman's  Response
Hello,

They are virtually the same thing. They are generally used as sleeping medicines in addition to their effect on colds and allergies, but some people have atypical responses to them and have sleeplessness.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Matt Wachsman, Addiction Medicine Specialist
I find this answer helpful

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Do Benadryl And Diphenhydramine Cause Sleeplessness?

Hello, Benadryl (brand) and Diphenhydramine (generic) are the same. It can cause drowsiness (often transient); sedation but unlikely to cause sleeplessness. Check the date of expiry. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Tushar Kanti Biswas, Internal Medicine Specialist