is my continuing constipation likely caused by the amiodarone I am taking ? I had very normal and regular bowel habits until I started amiodarone and then started having constipation. When my dose of amiodarone was increase recently, I started to have significant lower back distress, that was aleaviated with bowel movement. Movements have gone from about 1 per day to 1 everyother day, sometimes to the next day. Amiodarone is prescribed for me for idiopathic AF. When initially on Ami, at 400 mg/day, constipation was significant (no stool for 2-4 days then very hard) As dose reduced to 100 mg/day stool issues only needed to use stool softener to have normal 1 bm per day. when dose uped due to break thru AF, stool activity reduced in frequency You should also know I had spinal surgery (L3-L5 and S1 fusion) in early March 17 started ami about may 17. Had constipation due to opiodes immediately post surg. Stopped all opiodes due to no need, pain controlled by ibuprophen within 1 week post hospital stay. Constipation returned within 1-2 weeks post initiation of amiodorone.