There is no significant drug interaction among metoprolol, lisinopril and alcohol. You can consume alcohol/beer/wine occasionally. But remember, alcohol consumption is responsible for increasing the risk of fatty liver disease, hepatic fibrosis, hepatitis, liver cirrhosis, certain cancers, raised blood pressure, stroke, and peptic ulcer. It also increases the risk of many family, work and social problems. So be cautious and take care. Also adopt lifestyles which would help you in controlling blood pressure. Advice 1. Regular exercise at least 30 minutes for 5 days in a week. The best types of exercise for lowering BP include walking, jogging, cycling, swimming or dancing. 2. Eating a diet that is rich in whole grains, fruits, vegetables and low-fat dairy products and skimps on saturated fat and cholesterol 3. Consume less salt 4. Avoid smoking, alcohol, coffee and caffeinated beverages 5. Lose extra weight if you are overweight and keep your body mass index between 19 and 25. BMI is calculated by formula BMI = Weight in Kilograms / (height in meters x height in meters) 6. Reduce your metal stress because stress activates sympathetic system and increases BP 7. Measure your BP regularly and be in touch with your doctor I hope this information will help you. I will be happy if you ask another question Thank