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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Nuplazid Cause Impaired Thoughts And Memory Issues?

My friend has just been put on newdrug nuplavid . she has Leuey Body demenia and the doctor wanted to try nulavid . After 2 days on the nuplavid My friend became very confused and did not recognize her husband even. She had taken this med twice daily for only 3 Days. Could this new drug nuplavid have. Caused this???
Thu, 19 Jan 2017
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General & Family Physician,  's  Response
Hi,

Yes it may cause confusion and memory issues. Nuplazid (Pimavanserin) is a selective serotonin inverse agonist (SSIA) approved for the treatment of hallucinations and delusions associated with psychosis associated with Parkinson’s disease.

Its most common side effects include swelling in the legs or feet due to accumulation of excessive fluid, nausea, confusion, constipation, and changes to normal walking, abnormal state of mind (confused state) and memory impairment. It may also cause QT interval prolongation which may increase the risk of ventricular arrhythmia.

Hope these answer your query. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali
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Does Nuplazid Cause Impaired Thoughts And Memory Issues?

Hi, Yes it may cause confusion and memory issues. Nuplazid (Pimavanserin) is a selective serotonin inverse agonist (SSIA) approved for the treatment of hallucinations and delusions associated with psychosis associated with Parkinson’s disease. Its most common side effects include swelling in the legs or feet due to accumulation of excessive fluid, nausea, confusion, constipation, and changes to normal walking, abnormal state of mind (confused state) and memory impairment. It may also cause QT interval prolongation which may increase the risk of ventricular arrhythmia. Hope these answer your query. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali