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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Continous Oncotrex Usage For Psoriasis Harmful?

I am on Oncotrex (15mg) for the last couple of years. Can I know the side effects of this medicineAge-42, Height-168 cms, weight- 75kg.
Medical History: I have been suffering from psoriasis for the last 27 years and I have tried all sorts of medicines. I started taking oncotrex 2 years back and I had dramatic results but again my skin condition got aggravated and though I am still continuing this medicine, the lesions are still there but under control. How long will I have to take this medicine, I do not know. I want to know the damage it can cause because of the continued usage.
Mon, 28 Jul 2014
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Dermatologist 's  Response
Hello,

Welcome to healthcare magic.

Oncotrex is methotrexate, a very effective drug in the treatment of psoriasis.

However, this has to be taken under the supervision of a dermatologist. It is a toxic drug which could cause side effects.

The most significant side effect is liver damage. It can cause significant damage, which if undetected can prove fatal. The total dosage of methotrexate, hence should not cross more than 1500-2000 grams. This is monitored by the treating doctor and is given very judiciously during flares and is altenated with other drugs/ phototherapy.

Other side effects include bone marrow suppression, lowering of blood counts and triggering of infections.

Please consult a dermatologist and get your blood counts, liver function test and chest X ray done to rule out side effects.

Do not take this drug unsupervised.

Hope this helps.

Take care.
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Does Continous Oncotrex Usage For Psoriasis Harmful?

Hello, Welcome to healthcare magic. Oncotrex is methotrexate, a very effective drug in the treatment of psoriasis. However, this has to be taken under the supervision of a dermatologist. It is a toxic drug which could cause side effects. The most significant side effect is liver damage. It can cause significant damage, which if undetected can prove fatal. The total dosage of methotrexate, hence should not cross more than 1500-2000 grams. This is monitored by the treating doctor and is given very judiciously during flares and is altenated with other drugs/ phototherapy. Other side effects include bone marrow suppression, lowering of blood counts and triggering of infections. Please consult a dermatologist and get your blood counts, liver function test and chest X ray done to rule out side effects. Do not take this drug unsupervised. Hope this helps. Take care.