Hi, my dentist said that a higher weed tolerance could make IV sedation less successful, and difficult to remove my wisdom teeth, is this true? If my tolerance isn t high will it still be a problem? Will I really not fall asleep completely? I smoke due to my anxiety and insomnia, and since regular insomnia medication does not work for me I was wondering how effective IV sedation was. How soon exactly should I not smoke before? 24-48 hours or more? I know of the possible harms of marijuana, so if you can, and still be in your right conscious, I d really appreciate just answering this question.