Hi Intake of Pepcid does not help much to treat gallbladder pain. Pepcid is effective only in suppressing the acid production in the stomach thus relieving the symptoms of upper abdominal pain, dyspepsia, reflux disease, etc. Nexium is more effective in suppressing the acid production hence it is preferred treatment of acidity related issues mentioned above. For the immediate relief of gallbladder pain you need to take antispasmodic drugs like buscopan, etc. I advise you to get an abdominal ultrasound scan done to find out the cause of gallbladder pain. Meanwhile avoid eating fatty meals, alcohol or its beverages. Hope this will