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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Taking Depakote And Lamotrigine Cause Skin Rashes?

I have complex partial seizures and have been treated with a combination of meds including Depakote and now LAMOTRIGINE. The seizures seem to be under control but, I now have developed skin rashes. My doctor has changed my doses from 100 mg twice a day to 50 mg twice a day. Could this be from a reaction with other meds. ?
Thu, 12 Jul 2018
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General & Family Physician,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Skin rash is a side effect of Lamotrigine.
Since you say that you have strated taking lamotrigine lately, in my opinion the skin rash is caused by that .
I higly recommend you to go to the ER and consult a neurologist, for a physical examination of the rash and to decide changing the medication.
Meanwhile you can use Loratadine once daily and calamine lotion for local relief.


Hope I have answered your query.
Let me know if I can assist you further.
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Does Taking Depakote And Lamotrigine Cause Skin Rashes?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Skin rash is a side effect of Lamotrigine. Since you say that you have strated taking lamotrigine lately, in my opinion the skin rash is caused by that . I higly recommend you to go to the ER and consult a neurologist, for a physical examination of the rash and to decide changing the medication. Meanwhile you can use Loratadine once daily and calamine lotion for local relief. Hope I have answered your query. Let me know if I can assist you further.