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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Done Dialysis For Renal Failure. Had Abnormal CPK. Due To Mcardles Disease?

My 19 year old daughter was hospitalized with cpk 350,000 resulting in renal failure in which she required dialysis 3 times. Her kidneys began to function again. We are awaiting to see a specialist in a neuromuscular group. Awaiting muscle biopsy for diagnosis. She recently after 2 mo from onset of it all has cpk of 298 and normal kidney function test results . In diseases such as mcardles disease does the cpk level fluctuate or does it normally remain elevated.
Mon, 14 Oct 2013
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General & Family Physician,  's  Response
Hi there,
Thank you for your question.
Raised CPK can have many causes, these include injury to the muscles, high fever, inflammation of the muscles called as myositis, McArdle's disease also causes high CPK levels.
In any condition the levels of CPK can fluctuate and since she was dialysed so the CPK must have been removed from the blood via dialysis so that could be the reason why it is not raised anymore.
Such a high CPK does require further testing such as a muscle biopsy etc to determine exaclty whats causing it and then to treat the condition accordingly.
Kindest Regards
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Done Dialysis For Renal Failure. Had Abnormal CPK. Due To Mcardles Disease?

Hi there, Thank you for your question. Raised CPK can have many causes, these include injury to the muscles, high fever, inflammation of the muscles called as myositis, McArdle s disease also causes high CPK levels. In any condition the levels of CPK can fluctuate and since she was dialysed so the CPK must have been removed from the blood via dialysis so that could be the reason why it is not raised anymore. Such a high CPK does require further testing such as a muscle biopsy etc to determine exaclty whats causing it and then to treat the condition accordingly. Kindest Regards