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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Had Hyperatrophy Of The Endometrium. Got Surgically Removed. What Is The Cause Behind It?

i want to ask you doctor awoman has 50 years old and she had ahyperatrophy of the endometrium
a pathological examination was done after surgical removal of the endompetrium and the endometrium was completely benign and ther was no atypia by the way i am adentist and iread that women after the age of 50
the have hyperatrophy of the endometrium because of estrogen secreted from the adrenal gland and some other sites of the body 2 weeks after surgery the thickness of the endometrium is 12 cm (thick) i think should this woman be given progestrone hormone to prevent the hyperatrophy she was given tamoxifen drug for breast cancer treatment for 6 years but ithink that there is no relathionship between tamoxifen and hyperatrophy because she did not use tamoxifen since 1 year after the curetage surgery why there is ahyoeratrophy (12 cm) what is your opinion by the way i am adentist and ihave some informations about gynecology and woman hormones
Thu, 13 Jun 2013
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Oncologist, Radiation 's  Response
Hi,
Endometrial hyperplasia and hypertrophy is somewhat different anyway the exact histopathological diagnosis is preferable. Estrogen plays a role in endometrial hyperplasia. Breast cancer patient should have an annual gynaecological check up to rule out the same. The clinical trials like ATAC, ATLAS has reported about it. But chance of malignancy is less. So you should better follow the normal breast cancer follow up protocol.
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Had Hyperatrophy Of The Endometrium. Got Surgically Removed. What Is The Cause Behind It?

Hi, Endometrial hyperplasia and hypertrophy is somewhat different anyway the exact histopathological diagnosis is preferable. Estrogen plays a role in endometrial hyperplasia. Breast cancer patient should have an annual gynaecological check up to rule out the same. The clinical trials like ATAC, ATLAS has reported about it. But chance of malignancy is less. So you should better follow the normal breast cancer follow up protocol.