Not to mind Razwell. He s in love with the idea that cholesterol has NO bearing on heart disease in a good way or a bad way, regardless of how high you cholesterol is, or whether you are using medicine, lowering it with natural remedies or lowering it with diet and exercise. Don t take his rudeness personally - he was actually relatively pleasant in this case. At least he didn t call you a stinky butthole. He most assuredly will vote thumbs down on my answer as he does for nearly all of my answers - and perhaps rant against me with one of his other identies...(sigh). Despite his rantings, the data do not support his position. Ancedotally, I treat heart attack patients in the hospital - almost every single patient has VERY elevated cholesterol numbers. If you lower your cholesterol to goal then you will see few events and reduced severity of events - and by events I mean, heart attack, stroke claudication problems (blockages in arteries in the legs), and major organ stenosis - like the kidney. Now for your question - lycopene has been show to be a good antioxidant but does not lower cholesterol per se. Fish oils and niacin have been shown to be effective in regard to lowering cholesterol/triglycerides. I hope this helps. Good luck.