hi, my 74 year old grandmother has multiple myloma. currently she is in severe pain, that started in her abdomen, then went to her lower back, she has two dark squares in the middle of her back, they are not raised, and are a little itchy, she said she has painful urination , she recently had loose stools that she thinks is related to prune juice, do you have any suggestions of what this could be? urinary tract infection perhaps?