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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Seizures Caused By Chemo, Nausea, Dizziness. Been On Lamotrigine. Side Effects?

Hi, I have been on lamotrigine since Jan. 28 and got up to 100 mg twice per day as of Feb.18. I am having bad side effects and feel I need to quit this drug. I understand I need to decrease it gradually the same way I started it. I need to know if I can accelerate this and not take 4 weeks to get off it. I went on it to control seizures caused by chemo . I only get one or two a year, and have never had one when I was awake, but only in my sleep. My doctor is away for the next 6 weeks and the pharmacist can t or won t answer this question. I live alone in a rural area and am too dizzy and nauseous to drive anywhere. Thank you for your time. Shannon
Fri, 28 Jun 2013
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Neurologist,  's  Response
Hi,

Thank you for posting your query.

First of all, you do not require long term antiepileptic drugs, if your seizures were chemo related.

I agree with you that lamotrigine should be gradually tapered off and stopped. Typically, you can reduce 25% of the dose per week and you can come off it in four weeks time.

Best wishes,
Dr Sudhir Kumar MD DM (Neurology)
Senior Consultant Neurologist
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Have Seizures Caused By Chemo, Nausea, Dizziness. Been On Lamotrigine. Side Effects?

Hi, Thank you for posting your query. First of all, you do not require long term antiepileptic drugs, if your seizures were chemo related. I agree with you that lamotrigine should be gradually tapered off and stopped. Typically, you can reduce 25% of the dose per week and you can come off it in four weeks time. Best wishes, Dr Sudhir Kumar MD DM (Neurology) Senior Consultant Neurologist