Hello, I am concerned about my husband. He has Krohn's and uses Humira injections every other week. Since Sunday, he has had a fever of around 101. He is taking ibuprophen for his fever. He is dealing with sweating spells when the ibuprophen wears off. Over the past two weeks, he has developed eczema spots on his arm and a large dry area on his upper back. I have heard of individuals having adverse reactions to Humira after a few years. This is his third or fourth year using this treatment for his Krohn's.