Hi, i am just wondering how long it takes for duromine to start having a weight loss effect? i have been taking it for for 6 days now and i am scared it's not working! the 1st 3 days i had no appetite what-so-ever and had to force myself to eat brekky, lunch and dinner (didn't want to go into starvation mode) and only slept for 2 hours each night. But ever since the 4th day i have felt nothing! no appetite reduction, i'm sleeping fine and wouldn't say i have any extra energy. I haven't been weighing myself as i don't want to become obsessed by the 'number' but i ended up doing it today after lunch (which i know won't give me an accurate reading) but if i subtract say 2kg from the food and liquid consumed throughout the day i pretty much have stayed the same weight from day 1!!!!!! shouldn't i have seen some change by now? when is it supposed to kick in? i am feeling so desperate nothing seems to work for me! i am the healthiest eater, i eat tiny portions and avoid junk food and i go to the gym 3 days a week plus walk the dog twice a day everyday.