I suffer from weather related migraines, during the spring/summer months it can be up to 5 a week. They are triggered most noticeably by rainfall, I can feel oncoming weather patterns 24 hours before they arrive. I generally have a 72 hour ocular pain (pre-drome,migraine,pro-drome?), and 30 minutes prior to rainfall I begin to yawn uncontrollably. To treat it I use 2 extra-strength Advil migraines softgels every 4 hours, this aborts the migraine 75% of the time with rest. The other 25% are generally introduced during sleep, I wake up in full nauseated migraine mode (12 hours of hell as I call it). The only effective medication I have found in 20 years are the Imitrex injections, treatment is usually 2 separate injections that are 4 hours apart. This treatment sadly only works about 75% of the time, which leaves me questioning my reasons to live the other 25%. A severe episode for me is typically 12 hours, the throbbing pain is worsened immensely by light, sound, movement, bending over. I tend to vomit for the first 6-8 hours (I vomit immediately after an injection also), the pain becomes tolerable after about 12 hours. Sweating is a big issue, as generally I am shivering at the same time; this usually stops when the vomiting does. I also take Amytriptiline and Topiramate which has helped reduced the number/severity. My lower lumber has deteriorated over the years from the constant bending/vomiting, it is now a fused mess that only worsens with each migraine. I know I cannot physically do this for another 20 years, what options are there out there for me?