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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can severe Pituitary Adenoma Be Treated?

Hi Doc, I am a nurse with a 76 year old husband who may have a pituitary adenoma. He is being worked up now. my question: if he elects not to have surgery for this (he is scared to death), what is the likelihood that treatment with somatostatin analogs would bring about a significant lowering of his GH? Thanks, Tracy
Fri, 31 Mar 2017
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General & Family Physician,  's  Response
Hi Tracy, thanks for your question and I'm glad to help with your concerns.

A general rule in endocrine surgery is that all growth hormone-secreting pituitary adenomas are treated surgically. Somatostatin analogues are only prescribed as post-operative adjunctive treatment.

After surgery for growth hormone-secreting pituitary adenomas, radiotherapy and medical therapy are instituted to further reduce growth hormone secretion.

So, i'm sorry but surgery is the definitive treatment for your husband.

I'd be glad to hear from you if you've got more questions or need more clarity.

Best regards.
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How Can severe Pituitary Adenoma Be Treated?

Hi Tracy, thanks for your question and I m glad to help with your concerns. A general rule in endocrine surgery is that all growth hormone-secreting pituitary adenomas are treated surgically. Somatostatin analogues are only prescribed as post-operative adjunctive treatment. After surgery for growth hormone-secreting pituitary adenomas, radiotherapy and medical therapy are instituted to further reduce growth hormone secretion. So, i m sorry but surgery is the definitive treatment for your husband. I d be glad to hear from you if you ve got more questions or need more clarity. Best regards.