Hello, Your boyfriend developed a bump on his penis and presently he has itching and discomfort. An itchy penis is most commonly caused by skin infections, chemicals used in hygiene products. It may be also a symptom of sexually transmitted disease. Sexually transmitted viral infections like herpes, can cause penile itching, there may also be blistering and painful penis bumps. Human Papilloma Virus (HPV) causes itchy genital warts. gonorrhea, chlamydia and UTI is a viral infection and results in itchy genital warts. You and your boyfriend is suggested to get clinically examined by a Urologist, get Urinalysis (R/E and C/S) and STD tests done, if positive results are obtained, you will be treated with antivirals / antibiotics. In the meantime, take care of your genital hygiene. Wear soft cotton clothes. In case of itching he can apply hydrocortisone ointment on the area affected. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Nupur K., General & Family Physician