I had been on generic for serzone for years. Also take 1mg zanax 2x a day. I have suffered from anxiety. Mom got very ill, and I started to feel depression along with increased anxiety. My counselor prescribed first 10 mg of trintellix, then 20. 20mg makes me wacky. I am on the 10mg. feel like I want to punch someone everyday. cant relax etc. Mom passed Dec. 18th, 2016. still struggling with that, but..... feel almost like I am in a fog most times. I feel it is the trintellix. Even though I felt that the serzone was not effective anymore, at least I did not have this anger issue, and inability to feel happy about anything. I almost don t care. feel racy at times. I want to go back on serzone. counselor wants to me to wait, as I have new medical issues. one being hypothyroid, which she feels is causing my new symtoms. I am going to be 60 years old. can you help me out? Cindy