Hi doctor I am a type 1 diabetic with the following conditions, I have pulmonary hypertension, stage 2 renal failure, sever gastric paresis at (78%) neurological condition (similar to ms but has not been identified as of yet - I am wheel chair bound have a pheochromocytoma tumor. I am on 2 liters of O2 with exertion. I am in constant pain to some extent because of under lying condition I have been referred to a pain specialist who has suggested. Botox to reduce the constant headaches. I have read some literature on line that indicates that the with breathing problems and a neurological condition refrain from this treatment. I currently only use excedrin which does little for the pain