My grandaughter has had neuroblastoma cancer for 4 years. They had had her increase her Estradiol patch from 1/3 to 1/2 about 2 1/2 weeks ago. She has been crying everyday the last two weeks. She has had an virial infection and after going to her peditrician was put on amoxicilian. Do you think the increase in the patch could make her emotional state go out of wack? She is crying hours everyday. Help?