Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Mesenteric panniculitis is a rare disease that affects the part of the mesentery that contains fat cells. Most people with mesenteric panniculitis don’t need treatment. Your doctor will monitor your symptoms and may do repeat CT scans to see if the inflammation is getting worse. Often, mesenteric panniculitis will go away on its own within a few weeks or months. If your symptoms bother you or they cause complications, your doctor will give you medicine to bring down inflammation in your body. Many of the drugs used to treat this condition work by suppressing the overactive immune system response. Corticosteroid drugs are often used to treat mesenteric panniculitis. Other medications to use are Azathioprine, Colchicine, Cyclophosphamide, Infliximab, Naltrexone, Pentoxifylline, Thalidomide, etc. Please consult your treating doctor he will examine and treat you accordingly. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Penchila Prasad Kandikattu