Hi my cardiologist had increased the dosage from 10 mg of cilacar to 20 mg cilacar , Eptus T 10/25 in place of Tide 5 mg along with Cardivas 12.5 + 6.25mg and clopilet A 75 mg. I had undergone CABG ( triple vessel block) 5 grafting in February 2011. My recent 2D color Doppler Echogram shows EF 35 % FS16% and impression : Global hypokinesiaof LV with accentuated hypo kinesiology thinning of inferoposterior segments Dilated LV / moderately severe LV dysfunction / No LV clot / stroke volume61ml. Cardiac output 3.77 L/min. / 2+ mitral regurgitation 2+ both Aortic Tricuspid regurgitation / mild to moderate Pulmonaryartery hypertension/ RA ,RV normal in size and adequate RV function no PE. Will you please as to whether the modified drugs and the dosage are essentially required as I am comfortable with earlier dosage of medicines. I already have muscle weakness and muscular pain and my diabetes levels gone up but now brought to control with antidiabetic drug metformin + glitizide and 10 - 12 units of humalog in the morning and Lantus 100 in the night. Looking forward to your expert medical opinion and guidance.