Hi,I am Dr. Shanthi.E (General & Family Physician). I will be looking into your question and guiding you through the process. Please write your question below.
How Can Severe Pain In The Joints And Muscles Be Treated?
I cannot take statins because I get severe muscle and joint pain. Additionally statins gave me only an insignificant response at lowering my cholesterol LDLs. So I quit taking statins five months ago; within one week my pain vanished. I ve been taking self injections of alirocumab (praulent), 150 mg/ml, for four months. My LDL levels plummeted by nearly 50% within two months. However I have been getting increasing muscle pain in my arms, hands and feet for the past two months. I get a negative test response for RA. Any suggestions?
Alirocumab has higher rates of myalgia as compared to statin. Dose should be adjusted to achieve a target level of low-density lipoprotein (LDL) cholesterol level of 70 mg per deciliter (1.8 mmol per liter).
Reported multi-centred trial dosage - alirocumab subcutaneously at a dose of 75 mg every 2 weeks.
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How Can Severe Pain In The Joints And Muscles Be Treated?
Hi, Alirocumab has higher rates of myalgia as compared to statin. Dose should be adjusted to achieve a target level of low-density lipoprotein (LDL) cholesterol level of 70 mg per deciliter (1.8 mmol per liter). Reported multi-centred trial dosage - alirocumab subcutaneously at a dose of 75 mg every 2 weeks. Check your serum CK (creatine kinase) level. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Tushar Kanti Biswas, Internal Medicine Specialist