I have been fighting sinusitis since a few days prior to Labor Day. I ve taken zithromycin and a pack of prednisone. I also use the Nettipot, have a humidifier in my house, Sudafed, Mucinex, Zyrtec, Singular, Patanase and a multi-vitamin. I ve seen my doctor three times. The first time I was given zithromycin. 4 days after completing it I went back because I wasn t any better and my lymph nodes were sore and swollen by then. I took 6 days of prednisone. I went back 3 days after finishing it and I m still tired (extremely hard time waking up in the mornings), sore chest & upper back between the shoulder blades, swollen and very tender lymph nodes, extreme facial discomfort and shortness of breath (especially if I walk up some stairs or talk a lot at one time). The nurse said my oxygen levels were good, along with other vitals. I have an on and off again low grade fever (below 100) but my usual body temp is 97.3-97.7. I have no desire to eat because when I do I feel more pressure in my chest and right below my sternum. A few nights in the past week it s been uncomfortable to sleep on my left side because it s uncomfortable near the lower portion of my ribs. This third time I visited my doctor she put me on Levaquin for 10 days...this is day 4. I haven t noticed any difference at all. Any suggestions on what I should next???