Treatment overview includes : The treatment of mastocytosis depends on the type, the symptoms of the disease, its extent, and the person’s overall health. In many cases, different types of doctors often work together to create a patient’s overall treatment plan that combines different types of treatments. This is called a multidisciplinary team. Cancer care teams include a variety of other health care professionals, such as physician assistants, nurses, social workers, pharmacists, counselors, dietitians, and others. There is no cure for mastocytosis, although several treatments can be used to relieve symptoms and remove a mastocytoma (see the Introduction section). Descriptions of the most common treatment options for mastocytosis are listed below. Take time to learn about all of your treatment options and be sure to ask questions about things that are unclear. Talk with your health care team about the goals of each treatment and what you can expect while receiving the treatment. Learn more about making treatment decisions. Managing symptoms: An important part of treating mastocytosis is controlling a person’s symptoms. One important way to do this is to avoid anything that may cause mast cells to release histamine. This may include extreme temperatures, alcohol, emotional stress, insect bites, and certain medications. For example, nonsteroidal anti-inflammatory drugs (NSAIDs) should be used with caution because these drugs may trigger the release of histamine and can cause severe reactions or an attack. Doctors may also recommend the following treatments to help relieve mastocytosis symptoms. Antihistamines. Antihistamines help relieve itching, flushing, and other skin reactions. Steroids. Steroids may be used to reduce the size of skin lesions. Epinephrine. People with mastocytosis often carry a syringe of epinephrine, a hormone made by the adrenal glands, in case they need to treat a severe allergic reaction. Other medications. Other medications can help relieve diarrhea and stomach pain. Ultraviolet light. Sometimes, exposing the skin rashes to a source of ultraviolet (UV) light can help relieve symptoms of cutaneous mastocytosis. Surgery Surgery may be performed to remove lesions, such as a mastocytoma. Many surgeries on the skin can be performed quickly and easily. Before surgery, talk with your health care team about the possible side effects from the specific surgery you will have. I hope you happy with information kindly rate it. thank you.