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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Is Down S Syndrome Diagnosed?

I want to ask questions about Down s Syndrome Screening ,what Biomarker are used for ? I m confused Some research says Total hCG or free β-hCG and some just says free β-hCG, are they the same? What is the difference between HCG 、 free beta HCG 、Total hCG and Total beta HCG? thank you.
Mon, 3 Sep 2018
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  Anonymous's Response
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Hi,

For screening down's syndrome, we test for free Beta HCG, unconjugated estriol and total inhibin. All of these together is known as the quad screen.

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How Is Down S Syndrome Diagnosed?

Hi, For screening down s syndrome, we test for free Beta HCG, unconjugated estriol and total inhibin. All of these together is known as the quad screen. Hope I have answered your query. Let me know if I can assist you further.