Dear sir Meftormin hydrochloride belongs to group of insulin sensitizers. which increases the insulin utilization of endogenously produced insulin. Metformin is indicated in type 2 diabetes, where the raised blood sugars are due to increased insulin resistance. In obese type 2 diabetes reducing insulin resistance is the main modality of treatment. Insulin shots might not be needed If there is absolute deficiency of insulin which is produced endogenously, then you need to give insulin shots rather than metformin. There are individual drug indication and contraindications for each patients. We cannot compare the efficacy of the drugs by comparing them Thanks