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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Cure MPGN Disease?

Hi,

This is venkat, ( Male, age 33 yrs) , suffering from MPGN since last 4 years and on medication ( Atorva 10mg, Losar 25mg & Ecosprin 75mg) but recently my creatinine levels are increasing day-by-day. now its 1.6 mg/dl. So my Dr suggested steroid ( Omnacortil 40mg - 2 tabs per day ) on alternate days. please let me know whether i am taking correct medicine for the disease or any perminant fix available for this disease in medical history ?

Thanks,

Venkat.

Mon, 8 Aug 2016
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Nephrologist,  's  Response
Dear venkat,MPGN is an umbrella term which includes so many conditions. Few conditions have specific treatment. First of all you should be checked for hepatitis C infection and other common conditions that can cause MPGN. It also could be due to something called complement abnormalities where prognosis is not so good. Regarding omnacortil,your nephrologist is doing right thing.In rapidly progressive situation a trial of omnacortil for a period of 6 months is common practice. For your kind information I'm telling you that even after Transplantation chances of recurrence is high. So your disease subtype should be analyzed prior to therapy. Now lot of research is going on this condition. Hopefully we may get new medicines in near future. Along with these medications take sodium bicarbonate and calcitriol medicines if not taking. All the best.
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How To Cure MPGN Disease?

Dear venkat,MPGN is an umbrella term which includes so many conditions. Few conditions have specific treatment. First of all you should be checked for hepatitis C infection and other common conditions that can cause MPGN. It also could be due to something called complement abnormalities where prognosis is not so good. Regarding omnacortil,your nephrologist is doing right thing.In rapidly progressive situation a trial of omnacortil for a period of 6 months is common practice. For your kind information I m telling you that even after Transplantation chances of recurrence is high. So your disease subtype should be analyzed prior to therapy. Now lot of research is going on this condition. Hopefully we may get new medicines in near future. Along with these medications take sodium bicarbonate and calcitriol medicines if not taking. All the best.