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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Prevent Malaria Relapse?

dear SIR,

I have been infected by malaria (plasmodium vivax) on the month of jan.2011,after detection of malaria frm my blood test report i had been given few dosages of quinine i.e. both injectable and oral..after complete treatment i was fine for one month but again i got infected by same p.v. malaria parasite....according to doctor the disease might have relapsed..again i have been prescribed the same dosages of qunine ...but some what more in comparasion to that which i had given before...at present i am ok.. but i am worried whether the infection may occur again...is there any preventive measure or any medicine that i have to take so that it does not infect again..?...pls help ....
Mon, 1 Jun 2015
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General & Family Physician 's  Response
Hi
Thanks for your query.
I appreciate your concern for the recurrent malaria caused by Plasmodium vivax.
You need to take a course of oral Primaquine for 14 days.

Well Quinine is one of the most effective drugs used to treat Chloroquine resistant malaria caused by the plasmodium species. However, in case of Plasmodium vivax infection the parasites remain dormant in the liver for longer period of time, they are not killed by Quinine or other antimalarial drugs, hence responsible for the the recurrent infection and thus fever.

To eradicate/kill these parasites (hypnozoites) another medication Primaquine has to be taken orally for a period of 14 days.
This medication is contraindicated in patients with G6PD deficiency.

Consult a physician (internist is preferred) for the prescription.

Hope this answers your query.

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How To Prevent Malaria Relapse?

Hi Thanks for your query. I appreciate your concern for the recurrent malaria caused by Plasmodium vivax. You need to take a course of oral Primaquine for 14 days. Well Quinine is one of the most effective drugs used to treat Chloroquine resistant malaria caused by the plasmodium species. However, in case of Plasmodium vivax infection the parasites remain dormant in the liver for longer period of time, they are not killed by Quinine or other antimalarial drugs, hence responsible for the the recurrent infection and thus fever. To eradicate/kill these parasites (hypnozoites) another medication Primaquine has to be taken orally for a period of 14 days. This medication is contraindicated in patients with G6PD deficiency. Consult a physician (internist is preferred) for the prescription. Hope this answers your query. Rate this answer, if you are convinced.