Hi, Your symptoms of depression look really alarming. Therefore, in my opinion, you should take your treatment under guidance of your doctor. you are advised not to stop the treatment without consulting your doctor. If you have any problem, you should discuss it with your doctor. However, you should also note, that anti-depressive medicines may take some time, before you feel apparent beneficial effects. About TMS, one thing you should note, that its efficacy, negative or positive effects have not been evaluated yet with conclusive results. No effect is seen in obsessive compulsive disorder or schizophrenia with this procedure. Still, it is an FDA approved techniques, only in patients of major depressive disorder, who are not responding to usual treatment with anti-depressive drugs. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Satnarain Bansal, General & Family Physician