Hi dr. I havehot flashes, chills in the evening, frequent urination in small amount, bloody dischage , some discomfort at the lower back but not painful took 100 mg of macrobid for 3 days 2x a day but seems not wirkin, then dr gave me apo sulfatrim 800/160 mg 2x a day to be taken 7 days , 5 days have passed but still not too much improvement pls help