Hello Doctors, I am 33 years old, 5"3" and 118 lbs. I have rheumatoid arthritis since I was 14 years old. I take Arava and plaquanil for more than 10 years for the RA. I also take Amaryl for diabetes and Labetalol for High blood pressure. Five months ago I started Cimzia for RA. Three weeks ago I got Coxsackie virus. After the Coxsackie dried up a week ago, I developed Urticaria. With the urticaria I have been on and off my medications. My PCP believes that the urticaria might be triggered by the combination of Cimzia and Arava. On the other hand, my immunologist thinks that the urticaria is a consequence of the coxsackie virus. My blood tests seem to be normal, excluding my sugar which is over 200 because of the prednisone that I have been taken for the urticaria. I am also taking allegra, cingulair, zantac, zyrtec, and sometimes benadryl. However, my urticaria gets worse and worse. The patches and itchiness is indescribable. At this point, I don’t know what to do or what to take to control the symptoms of the urticaria. I went to the ER twice. The ER doctors control the urticaria symptoms while I am at the hospital but once I get back home, all symptoms persist. Assuming the urticaria is post viral (caused by coxsackie), how long does it usually last? On the other hand, If the urticaria is caused by the interaction of medications, should I cleaned up my system from the medicines and start from scratch. I have previously used a medication to clean up my system from Arava. Will that make the urticaria go away?