Hi, Weaning off Cymbalta (duloxetine) should be done under the guidance and supervision of a healthcare professional, as abruptly stopping the medication can lead to withdrawal symptoms. Here are some general guidelines that may be followed, but it s important to consult with your doctor for personalized advice and to discuss a tapering schedule that suits your specific situation: * Consult with your healthcare provider: Before starting the tapering process, discuss your desire to discontinue Cymbalta with your doctor. * Gradual tapering: Cymbalta should be tapered slowly to minimize the risk of withdrawal symptoms. Typically, this involves reducing the dosage gradually over several weeks or months. * Follow your doctor s instructions: Strictly follow the tapering plan provided by your doctor. This may involve reducing the dosage by a certain percentage or switching to a lower-strength formulation, such as capsules with smaller doses. * Monitor for withdrawal symptoms: During the tapering process, be aware of any withdrawal symptoms that may arise. These can include dizziness, nausea, headache, irritability, insomnia, and flu-like symptoms. If you experience any concerning symptoms, inform your healthcare provider. * Supportive care: Engage in self-care practices to support your overall well-being during the tapering process. This may include maintaining a healthy lifestyle, getting regular exercise, practicing stress-reduction techniques, and ensuring adequate sleep. * Regular follow-up: Stay in close communication with your doctor. They will monitor your progress, address any concerns or challenges, and provide ongoing support. Remember, everyone s experience with medication withdrawal can vary, and a personalized approach is crucial. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Muhammad Umer Farooq, General & Family Physician