I am 77 year old female. I have Asthma, COPD, CHF, GERD, CAD (mild). I've had 3 PE'so due to have broken my knee. My last stress test 2as "fantastic" according to cardiologist. I take Lasix for water retention. My ankles are not swollen. But I get very very tired doing very little. I get out of breath so that I talk haltingly. I have to lie down or sit. Just walking is difficult and I get out of breath. The pulmonologist didn't find anything wrong, neither did the primary care.