I am post post menopause...... I have multiple sclerosis and A-FIB... ulcer colitis, osteoarthritis, copper tunnel delayed gastric emptying ... Every night click clock work between 8-7 I get very hot and my face and ears are hot..... Them it will last 10-15 min and the I get cold. That will last all night..... Also i bruise for no reason..... They have rent all my blood work everything has come back normal my thyroid cholesterol every blood work you think they man came back normal before at a loss. When in wake up I am all sweaty... I go see my primary doctor in 2 weeks....... price would be great thank you very much Wendy Goodman