I had a bad reaction to brentuximab, after 5 days after 2nd infusion, of 3 I fusions 21 days apart, I went to a dermatologist, he said spongy dermititus is what the biopsy showed. The real got much worse, after about 65-75 days, I was put on prednisone 20 mg x2 a day for 10 days, then 1x aday for 20 days...still taking it. My oncologist said he would only continue the infusion, if rash is completly gone, and he would also give me a cortasteroid along with the brentuximab!