I had to be off Lyrica for a couple of weeks because my Insurance decided not to cover it anymore. After my Othro Surgeon and Family Practice Doctors had to appeal it they finally decided to cover it. I had gone the week before and paid over $400.00 for it. I take 300mg tid and have been on it for 3 years. I have had 5 back surgeries and have Fibromyalgia. It has been the best medicine for me going off it cold turkey just about made me crazy in more ways than one. The fibromyalgia just was horrible I missed several days of work not being able to get out of bed and walk. So I am back on it now for 2 weeks but a week ago I noticed that my hands hurt really bad the knuckles are swollen thinking I may have arthritis in the fingers. Could be being off the Lyrica and then started back cause any problems there? The knuckles are bruised also.