I have had issues with pravastatin sodium in the past,, I have been taking 40mg, but after finding blockages after a catheterization recently the prescription was increased to 80mg. In the last three weeks I have become increasingly debilitated in an area of my back,, L-5, that I have had problems with in the past. It started a few days after I started the new prescription. I was advised years ago after x rays that I had a hemisacralization of L 5.