I received the PCV 13 vaccine on the 16th of Dec. shortly thereafter I suffered from fatigue, muscle weakness, cold symptoms, increase in arthritis symptoms in joints that previously had not given me problems. In general I felt worse than the one time years ago when I did have pneumonia. I do have a compromised immune system. I have rheumatoid arthritis and osteoarthritis. These symptoms have continued. I think I'm better and then I'm exhausted and back in bed again. I feel like I'm losing my mind. I'm not a whiny person but this has just gone on too long. I never take flu shots. But was enc. to take the 2nd dose of this one.