I suffer from severe anxiety, agoraphobia, depression,COPD,( need to wear Trilogy at night) and oxygen 24/7. Dr. gave me samples of Deplin but I felt it disturbed sleep even more, I also have Neuropothy, 3 new lesions on my lungs,cancelled Broncoscopy, Probable EDS, possible PTSD. Need to leave in a few minutes to see Phyciatrist for monthly appt. She told me to order Deplin on line. I am a 66 yr. old female, other issues ,too many to mention